NCC-PS1-C1

Description

Cell line name NCC-PS-C1
Accession CVCL_C5Z2
Resource Identification Initiative To cite this cell line use: NCC-PS-C1 (RRID:CVCL_C5Z2)
Comments Part of: NCC sarcoma cell line panel.
                         Population: Japanese.
Doubling time: 39 hours (PubMed=36103079).
 Omics: SNP array analysis.
Derived from site: In situ; Popliteal fossa, hypodermis; UBERON=UBERON_0013069+UBERON_0002072.
Sequence variations
Mutation; HGNC; 1787; CDKN2A; Simple; p.Cys72Ter (c.216C>A); Zygosity=Unspecified (PubMed=36103079).
Mutation; HGNC; 7883; NOTCH3; Simple; p.Arg1873Cys (c.5617C>T); ClinVar=VCV000932356; Zygosity=Unspecified (PubMed=36103079).
Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (PubMed=36103079).
Disease Undifferentiated pleomorphic sarcoma (NCIt: C4247)
Undifferentiated pleomorphic sarcoma (ORDO: Orphanet_2023)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
STR profile

Source(s): PubMed=36103079

Markers:

Publications
PubMed=36103079; DOI=10.1007/s13577-022-00787-1
Akiyama T., Yoshimatsu Y., Noguchi R., Sin Y., Tsuchiya R., Ono T., Sugaya J., Kobayashi E., Yoshida A., Ohtori S., Kawai A., Kondo T.
Establishment and characterization of NCC-PS1-C1: a novel cell line of pleomorphic sarcoma from a patient after neoadjuvant radiotherapy.
Hum. Cell 35:2011-2019(2022)

Cross-references
Encyclopedic resources Wikidata; Q116049882