NCC-OS1-X2-C1

Description

Cell line name NCC-OS1-X2-C1
Synonyms NCC-OS1-C1; NCCOS1X2C1
Accession CVCL_VM08
Resource Identification Initiative To cite this cell line use: NCC-OS1-X2-C1 (RRID:CVCL_VM08)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line 　　　　　Encyclopedia – CCLE).
Part of: NCC sarcoma cell line panel.
Population: Japanese.
Characteristics: Established from a second generation xenograft established by 　　　　　subcutaneous injection in female SCID mice.
Doubling time: 29 hours (PubMed=29943355).
Omics: Deep proteome analysis.
Derived from site: In situ; Bone, distal femur; UBERON=UBERON_0004406.
Sequence variations
Mutation; HGNC; 1787; CDKN2A; Simple; p.His66Arg (c.197A>G) (p.Pro80Pro, c.240A>G); 　　　　　ClinVar=VCV000246117; Zygosity=Unspecified (DOI=10.2198/jelectroph.65.1).
Disease   Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
STR profile

　　　　Source(s): PubMed=29943355

　　　　Markers:

Publications
PubMed=29943355; DOI=10.1007/s11626-018-0274-2
Kito F., Oyama R., Sakumoto M., Takahashi M., Shiozawa K., Qiao Z., Sakamoto H., Hirose T., Setsu N., Yoshida A., Kawai A., Kondo T.
Establishment and characterization of novel patient-derived osteosarcoma xenograft and cell line.
In Vitro Cell. Dev. Biol. Anim. 54:528-536(2018)

DOI=10.2198/jelectroph.65.1
Noguchi R., Yoshimatsu Y., Ono T., Sei A., Kondo T.
Proteogenomic approach to drug targets in osteosarcomas with different original sites.
J. Electroph. 65:1-11(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VM08
DepMap; ACH-002778
Encyclopedic resources Wikidata; Q95992540